Hydroxyethyl starch 130/0.4

Hydroxyethyl starch 130/0.4 is made from waxy corn starch (amylopectin) as raw material, mild acidolysis, and hydroxylation with ethylene oxide (or 2-chloroethanol) under alkaline conditions. , is a blood volume expander API.

Hydroxyethyl starch 130/0.4 is a blood volume expander used to treat and prevent hypovolemia and acute isovolumetric hemodilution (ANH).

Constitute hydroxyethyl starch 130/0.4 into an injection solution and infuse it into the patient through intravenous infusion. The infusion should be slow and the patient should be observed closely (to prevent possible allergic-like reactions).

The maximum daily dose is based on body weight 33ml/kg. The daily dose and infusion rate should be determined based on the patient’s blood loss, maintenance or recovery of hemodynamic parameters, and dilution effect.

Molecular hydroxyethyl starch 130/0.4 is currently the most widely used product among several types of plasma-substitute products. However, for patients with certain health conditions, there are risks such as increased mortality, renal damage, and excessive bleeding. It should be based on the patient’s needs. Health conditions, use with caution after weighing the pros and cons, and pay close attention to the occurrence of adverse reactions in patients during use.